Two non-cytotoxic type 2 ribosome-inactivating proteins (Sambucus Sieboldiana lectin and Sambucus Nigra lectin) lead neurosphere cells to caspase-independent apoptosis
نویسندگان
چکیده
منابع مشابه
Flow Lectin Affinity Chromatography–A Model with Sambucus nigra Agglutinin
The study of proteomes has become an important way to assess changes occurring in disease conditions. Nonetheless, the dominance of highly abundant serum proteins significantly complicates the discovery and analysis of low-abundant glycoproteins that may constitute potential disease biomarkers. Several techniques have been used to perform serum proteome partitioning such as affinity chromatogra...
متن کاملSambucus nigra (Elderberry) Monograph
Introduction Sambucus nigra, or European elder, is a tall tree-like shrub, native to Europe, Asia, and North Africa, and naturalized in the United States. Various parts of the elder have long been used in traditional medicine as a diaphoretic, diuretic, astringent, laxative, and emetic. The berries were used traditionally as a food to make elderberry wine and pies, and as a flavoring or dye. Cu...
متن کاملAntidepressant activities of Sambucus ebulus and Sambucus nigra.
OBJECTIVE Many pharmacological activities have been reported in Sambucus (S.) genus. The aim of present study was to investigate antidepressant activities of different parts of S. ebulus and S. nigra. MATERIALS AND METHODS Antidepressant activity of methanolic extracts were evaluated by forced swimming test (FST) and tail suspension tests (TST) in male Swiss albino mice. RESULTS Extracts sh...
متن کاملFractionation of sialylated oligosaccharides, glycopeptides, and glycoproteins on immobilized elderberry (Sambucus nigra L.) bark lectin.
A new plant lectin from elderberry (Sambucus nigra L.) bark, which was shown by immunochemical techniques to bind specifically to terminal Neu5Ac(alpha 2-6)Gal/GalNAc residues of glycoconjugates, was immobilized onto Sepharose 4B (SNA-Sepharose) and its carbohydrate binding properties was determined using a series of standard compounds. Oligosaccharides, glycopeptides, or glycoproteins containi...
متن کاملEbulin 1, a nontoxic novel type 2 ribosome-inactivating protein from Sambucus ebulus L. leaves.
A novel type 2 ribosome-inactivating protein (RIP) that we named ebulin 1 has been isolated from leaves of Sambucus ebulus L. (Caprifoliaceae). In vitro ebulin 1 strongly inhibited protein synthesis by rabbit reticulocyte lysates, rat brain, and rat liver cell-free systems but did not affect in vitro plant nor bacterial protein synthesis. Ebulin 1 is composed of two subunits, a catalytic A subu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biomedical Research
سال: 2018
ISSN: 0976-1683
DOI: 10.4066/biomedicalresearch.29-17-3589